Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate

Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate

Abstract The double-ring AAA+ ATPase Pex1/Pex6 is required for peroxisomal receptor recycling and is essential for peroxisome formation. Pex1/Pex6 mutations cause severe peroxisome associated developmental disorders. Despite its pathophysiological importance, mechanistic details of the heterohexamer...

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Bibliographic Details
Main Authors: Maximilian Rüttermann, Michelle Koci, Pascal Lill, Ermis Dionysios Geladas, Farnusch Kaschani, Björn Udo Klink, Ralf Erdmann, Christos Gatsogiannis
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-41640-9

Internet

https://doi.org/10.1038/s41467-023-41640-9

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