The Antidiabetic Agent Metformin Inhibits IL-23 Production in Murine Bone-Marrow-Derived Dendritic Cells

Psoriasis is a chronic inflammatory skin disease, and its immune mechanism has been profoundly elucidated. Biologics targeting interleukin (IL)-23 have prevented the development of psoriasis. As major sources of IL-23, dendritic cells (DCs) play a pivotal role in psoriasis; however, the regulatory m...

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Bibliographic Details
Main Authors: Tomoyo Matsuda-Taniguchi, Masaki Takemura, Takeshi Nakahara, Akiko Hashimoto-Hachiya, Ayako Takai-Yumine, Masutaka Furue, Gaku Tsuji
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/10/23/5610