Predictive role of UCA1-containing exosomes in cetuximab-resistant colorectal cancer

Predictive role of UCA1-containing exosomes in cetuximab-resistant colorectal cancer

Abstract Background Primary or acquired resistance to cetuximab often occurs during targeted therapy in metastatic colorectal cancer (mCRC) patients. In many cancers, the key role of the long noncoding RNA (lncRNA) urothelial carcinoma-associated 1 (UCA1) in anticancer drug resistance has been confi...

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Bibliographic Details
Main Authors: Ying-nan Yang, Rui Zhang, Jing-wen Du, Heng-heng Yuan, Yan-jing Li, Xiao-li Wei, Xiao-xue Du, Shu-lin Jiang, Yu Han
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Cancer Cell International
Subjects:
UCA1
Exosomes
Cetuximab
Metastatic colorectal cancer
Biomarker
Online Access:http://link.springer.com/article/10.1186/s12935-018-0660-6

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http://link.springer.com/article/10.1186/s12935-018-0660-6

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