Key Factor Study for Generic Long-Acting PLGA Microspheres Based on a Reverse Engineering of Vivitrol<sup>®</sup>

Key Factor Study for Generic Long-Acting PLGA Microspheres Based on a Reverse Engineering of Vivitrol<sup>®</sup>

The FDA (U.S. Food and Drug Administration) has approved only a negligible number of poly(lactide-co-glycolide) (PLGA)-based microsphere formulations, indicating the difficulty in developing a PLGA microsphere. A thorough understanding of microsphere formulations is essential to meet the challenge o...

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Bibliographic Details
Main Authors: Yabing Hua, Zengming Wang, Dan Wang, Xiaoming Lin, Boshi Liu, Hui Zhang, Jing Gao, Aiping Zheng
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Molecules
Subjects:
PLGA microspheres
reverse engineering
Vivitrol<sup>®</sup>
generic naltrexone-loaded microspheres
critical process parameters
Online Access:https://www.mdpi.com/1420-3049/26/5/1247

Internet

https://www.mdpi.com/1420-3049/26/5/1247

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