SFRS11 Loss Leads to Aging-Associated Cognitive Decline by Modulating LRP8 and ApoE

Summary: RNA binding proteins, the key regulators in gene expression at the posttranscriptional level, remain largely uncharacterized with respect to aging and relevant cognitive deterioration. Here, we report that the levels of SFRS11 are substantially decreased in the prefrontal cortex (PFC) of ag...

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Bibliographic Details
Main Authors: Obayed Raihan, Afrina Brishti, Qin Li, Qilun Zhang, Dingfeng Li, Xiaohui Li, Qingyang Zhang, Zhongwen Xie, Jiali Li, Juan Zhang, Qiang Liu
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719307600