Mesoporous silica coated spicules for photodynamic therapy of metastatic melanoma

Mesoporous silica coated spicules for photodynamic therapy of metastatic melanoma

Abstract We report on the fabrication of mesoporous silicon dioxide coated Haliclona sp. spicules (mSHS) to enhance the delivery of the insoluble photosensitizer protoporphyrin IX (PpIX) into deep skin layers and mediate photodynamic therapy for metastatic melanoma in mice. The mSHS are dispersed sh...

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Bibliographic Details
Main Authors: Xuejiao Liang, Jialiang Zhang, Chi Zhang, Haojie Zhai, Ping Yang, Ming Chen
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Journal of Nanobiotechnology
Subjects:
SHS
Mesoporous silica
Melanoma
Photodynamic therapy
Skin delivery
Online Access:https://doi.org/10.1186/s12951-024-02471-y

Internet

https://doi.org/10.1186/s12951-024-02471-y

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