Mesoporous silica coated spicules for photodynamic therapy of metastatic melanoma
Abstract We report on the fabrication of mesoporous silicon dioxide coated Haliclona sp. spicules (mSHS) to enhance the delivery of the insoluble photosensitizer protoporphyrin IX (PpIX) into deep skin layers and mediate photodynamic therapy for metastatic melanoma in mice. The mSHS are dispersed sh...
Main Authors: | Xuejiao Liang, Jialiang Zhang, Chi Zhang, Haojie Zhai, Ping Yang, Ming Chen |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-04-01
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Series: | Journal of Nanobiotechnology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12951-024-02471-y |
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