Bisphosphonate-based hydrogel mediates biomimetic negative feedback regulation of osteoclastic activity to promote bone regeneration

Bisphosphonate-based hydrogel mediates biomimetic negative feedback regulation of osteoclastic activity to promote bone regeneration

The intricate dynamic feedback mechanisms involved in bone homeostasis provide valuable inspiration for the design of smart biomaterial scaffolds to enhance in situ bone regeneration. In this work, we assembled a biomimetic hyaluronic acid nanocomposite hydrogel (HA-BP hydrogel) by coordination bond...

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Bibliographic Details
Main Authors: Zhuo Li, Haixing Wang, Kunyu Zhang, Boguang Yang, Xian Xie, Zhengmeng Yang, Lingchi Kong, Peng Shi, Yuan Zhang, Yi-Ping Ho, Zhi-Yong Zhang, Gang Li, Liming Bian
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-07-01
Series:Bioactive Materials
Subjects:
Bisphosphonate
Hydrogel
Tissue engineering
Bone regeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X21005259

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http://www.sciencedirect.com/science/article/pii/S2452199X21005259

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