PACAP signaling is not involved in GTN- and levcromakalim-induced hypersensitivity in mouse models of migraine

Abstract Background Calcitonin gene-related peptide (CGRP) antagonizing drugs represents the most important advance in migraine therapy for decades. However, these new drugs are only effective in 50–60% of patients. Recent studies have shown that the pituitary adenylate cyclase-activating peptide (P...

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Detalhes bibliográficos
Principais autores: Song Guo, Charlotte Ernstsen, Anders Hay-Schmidt, David Møbjerg Kristensen, Messoud Ashina, Jes Olesen, Sarah Louise Christensen
Formato: Artigo
Idioma:English
Publicado em: BMC 2022-12-01
coleção:The Journal of Headache and Pain
Assuntos:
Acesso em linha:https://doi.org/10.1186/s10194-022-01523-8