Mechanism by which water and protein electrostatic interactions control proton transfer at the active site of channelrhodopsin.

Channelrhodopsins are light-sensitive ion channels whose reaction cycles involve conformation-coupled transfer of protons. Understanding how channelrhodopsins work is important for applications in optogenetics, where light activation of these proteins triggers changes in the transmembrane potential...

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Bibliographic Details
Main Authors: Suliman Adam, Ana-Nicoleta Bondar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6080761?pdf=render