SH2B1 promotes NSCLC cell proliferation through PI3K/Akt/mTOR signaling cascade

SH2B1 promotes NSCLC cell proliferation through PI3K/Akt/mTOR signaling cascade

Abstract Background Non-small cell lung cancer (NSCLC), the most prevalent type of human lung cancer, is characterized by many molecular abnormalities. SH2B1, a member of the SH2-domain containing family, have recently been shown to act as tumor activators in multiple cancers. The objective of this...

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Bibliographic Details
Main Authors: Shaoqiang Wang, Yingying Zheng, Zhiwei He, Wolong Zhou, Yuanda Cheng, Chunfang Zhang
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Cancer Cell International
Subjects:
SH2B1
Proliferation
AKT
NSCLC
Online Access:http://link.springer.com/article/10.1186/s12935-018-0632-x

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http://link.springer.com/article/10.1186/s12935-018-0632-x

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