Improved Olfactory Deposition of Theophylline Using a Nanotech Soft Mist Nozzle Chip

Currently, nasal administration of active pharmaceutical ingredients is most commonly performed using swirl-nozzle-based pump devices or pressurized syringes. However, they lead to limited deposition in the more active regions of the nasal cavity, especially the olfactory region, which is crucial fo...

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Bibliographic Details
Main Authors: Madeline X. Zhang, Frank Verhoeven, Pieter Ravensbergen, Stefan Kooij, Rick Geoffrion, Daniel Bonn, Cees J. M. van Rijn
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/16/1/2