Applications of CRISPR/Cas as a Toolbox for Hepatitis B Virus Detection and Therapeutics

Applications of CRISPR/Cas as a Toolbox for Hepatitis B Virus Detection and Therapeutics

Hepatitis B virus (HBV) infection remains a significant global health challenge, leading to chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma (HCC). Covalently closed circular DNA (cccDNA) and integrated HBV DNA are pivotal in maintaining viral persistence. Recent advances in CRISPR/C...

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Bibliographic Details
Main Authors: Anuj Kumar, Emmanuel Combe, Léa Mougené, Fabien Zoulim, Barbara Testoni
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Viruses
Subjects:
HBV
cccDNA
CRISPR/Cas
gene editing
diagnostics
Online Access:https://www.mdpi.com/1999-4915/16/10/1565

Internet

https://www.mdpi.com/1999-4915/16/10/1565

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