Thailandepsins are new small molecule class I HDAC inhibitors with potent cytotoxic activity in ovarian cancer cells: a preclinical study of epigenetic ovarian cancer therapy
<p>Abstract</p> <p>Background</p> <p>New treatment strategies are emerging to target DNA damage response pathways in ovarian cancer. Our group has previously shown that the class I biased HDAC inhibitor romidepsin (FK228) induces DNA damage response and has potent cytot...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-04-01
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Series: | Journal of Ovarian Research |
Subjects: | |
Online Access: | http://www.ovarianresearch.com/content/5/1/12 |