Aberrant DNA methylation in multiple myeloma: A major obstacle or an opportunity?

Aberrant DNA methylation in multiple myeloma: A major obstacle or an opportunity?

Drug resistance (DR) of cancer cells leading to relapse is a huge problem nowadays to achieve long-lasting cures for cancer patients. This also holds true for the incurable hematological malignancy multiple myeloma (MM), which is characterized by the accumulation of malignant plasma cells in the bon...

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Bibliographic Details
Main Authors: Catharina Muylaert, Lien Ann Van Hemelrijck, Anke Maes, Kim De Veirman, Eline Menu, Karin Vanderkerken, Elke De Bruyne
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
multiple myeloma
epigenetics
DNA methylation modifiers
MM cell plasticity
DNMTi
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.979569/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.979569/full

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