Co-culture pellet of human Wharton’s jelly mesenchymal stem cells and rat costal chondrocytes as a candidate for articular cartilage regeneration: in vitro and in vivo study

Co-culture pellet of human Wharton’s jelly mesenchymal stem cells and rat costal chondrocytes as a candidate for articular cartilage regeneration: in vitro and in vivo study

Abstract Background Seeding cells are key factors in cell-based cartilage tissue regeneration. Monoculture of either chondrocyte or mesenchymal stem cells has several limitations. In recent years, co-culture strategies have provided potential solutions. In this study, directly co-cultured rat costal...

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Bibliographic Details
Main Authors: Kaiwen Zheng, Yiyang Ma, Cheng Chiu, Yidan Pang, Junjie Gao, Changqing Zhang, Dajiang Du
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Stem Cell Research & Therapy
Subjects:
Human Wharton’s jelly-derived mesenchymal stem cell
Costal chondrocyte
Co-culture system
Chondrogenesis
Osteochondral defect
Cartilage regeneration
Online Access:https://doi.org/10.1186/s13287-022-03094-6

Internet

https://doi.org/10.1186/s13287-022-03094-6

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