Neuroprotective Roles of the Biliverdin Reductase-A/Bilirubin Axis in the Brain

Biliverdin reductase-A (BVRA) is a multi-functional enzyme with a multitude of important roles in physiologic redox homeostasis. Classically, BVRA is well known for converting the heme metabolite biliverdin to bilirubin, which is a potent antioxidant in both the periphery and the brain. However, BVR...

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Bibliographic Details
Main Authors: Bindu D. Paul, Andrew A. Pieper
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/14/2/155