Structure and function of molecular machines involved in deadenylation-dependent 5′-3′ mRNA degradation

In eukaryotic cells, the synthesis, processing, and degradation of mRNA are important processes required for the accurate execution of gene expression programmes. Fully processed cytoplasmic mRNA is characterised by the presence of a 5′cap structure and 3′poly(A) tail. These elements promote transla...

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Bibliographic Details
Main Authors: Qi Zhao, Lorenzo Pavanello, Mark Bartlam, Gerlof Sebastiaan Winkler
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1233842/full