Strontium modulates osteogenic activity of bone cement composed of bioactive borosilicate glass particles by activating Wnt/β-catenin signaling pathway

Strontium modulates osteogenic activity of bone cement composed of bioactive borosilicate glass particles by activating Wnt/β-catenin signaling pathway

There is a need for synthetic grafts to reconstruct large bone defects using minimal invasive surgery. Our previous study showed that incorporation of Sr into bioactive borate glass cement enhanced the osteogenic capacity in vivo. However, the amount of Sr in the cement to provide an optimal combina...

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Bibliographic Details
Main Authors: Xu Cui, Yadong Zhang, Jianyun Wang, Chengcheng Huang, Yudong Wang, Hongsheng Yang, Wenlong Liu, Ting Wang, Deping Wang, Guocheng Wang, Changshun Ruan, Dafu Chen, William W. Lu, Wenhai Huang, Mohamed N. Rahaman, Haobo Pan
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2020-06-01
Series:Bioactive Materials
Subjects:
Injectable bone cement
Bioactive borosilicate glass
Strontium
Signaling pathway
Bone regeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X20300396

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http://www.sciencedirect.com/science/article/pii/S2452199X20300396

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