Facile distribution of an alkaline microenvironment improves human bone marrow mesenchymal stem cell osteogenesis on a titanium surface through the ITG/FAK/ALP pathway

Facile distribution of an alkaline microenvironment improves human bone marrow mesenchymal stem cell osteogenesis on a titanium surface through the ITG/FAK/ALP pathway

Abstract Purpose Osseointegration at the titanium surface-bone interface is one of the key factors affecting the success rate of dental implants. However, the titanium surface always forms a passive oxide layer and impacts bone marrow–derived mesenchymal stem cell (BMSC) osteogenic differentiation a...

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Bibliographic Details
Main Authors: Chen-Xi Wang, Ting Ma, Ming-Yue Wang, Hou-Zuo Guo, Xi-Yuan Ge, Yu Zhang, Ye Lin
Format: Article
Language:English
Published: SpringerOpen 2021-06-01
Series:International Journal of Implant Dentistry
Subjects:
Dental implant
Titanium surface
Bone mesenchymal stem cells
Osteogenic differentiation
Microenvironment pH
Online Access:https://doi.org/10.1186/s40729-021-00341-y

Internet

https://doi.org/10.1186/s40729-021-00341-y

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