Microglial intracellular Ca2+ signaling as a target of antipsychotic actions for the treatment of schizophrenia

Microglial intracellular Ca2+ signaling as a target of antipsychotic actions for the treatment of schizophrenia

Microglia are resident innate immune cells which release many factors including proinflammatory cytokines, nitric oxide (NO) and neurotrophic factors when they are activated in response to immunological stimuli. Recent reports show that pathophysiology of schizophrenia is related to the inflammatory...

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Bibliographic Details
Main Authors: Yoshito eMizoguchi, Takahiro A. Kato, Hideki eHorikawa, Akira eMonji
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Calcium
Endoplasmic Reticulum
Microglia
Schizophrenia
BDNF
Antipsychotics
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00370/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00370/full

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