Fine tuning a logical model of cancer cells to predict drug synergies: combining manual curation and automated parameterization
Treatment with combinations of drugs carries great promise for personalized therapy for a variety of diseases. We have previously shown that synergistic combinations of cancer signaling inhibitors can be identified based on a logical framework, by manual model definition. We now demonstrate how auto...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-11-01
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| Series: | Frontiers in Systems Biology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fsysb.2023.1252961/full |