Agonistic and antagonistic roles for TNIK and MINK in non-canonical and canonical Wnt signalling.

Wnt signalling is a key regulatory factor in animal development and homeostasis and plays an important role in the establishment and progression of cancer. Wnt signals are predominantly transduced via the Frizzled family of serpentine receptors to two distinct pathways, the canonical ß-catenin pathw...

Full description

Bibliographic Details
Main Authors: Alexander Mikryukov, Tom Moss
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3439448?pdf=render