Fetal hemoglobin rescues ineffective erythropoiesis in sickle cell disease

Fetal hemoglobin rescues ineffective erythropoiesis in sickle cell disease

While ineffective erythropoiesis has long been recognized as a key contributor to anemia in thalassemia, its role in anemia of sickle cell disease (SCD) has not been critically explored. Using in vitro and in vivo derived human erythroblasts we assessed the extent of ineffective erythropoiesis in S...

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Bibliographic Details
Main Authors: Sara El Hoss, Sylvie Cochet, Auria Godard, Hongxia Yan, Michaël Dussiot, Giacomo Frati, Bénédicte Boutonnat-Faucher, Sandrine Laurance, Olivier Renaud, Laure Joseph, Annarita Miccio, Valentine Brousse, Mohandas Narla, Wassim El Nemer
Format: Article
Language:English
Published: Ferrata Storti Foundation 2020-08-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/9915

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https://haematologica.org/article/view/9915

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