Anti-cancer immune effect of human colorectal cancer neoantigen peptide based on MHC class I molecular affinity screening

BackgroundTumor antigen peptide vaccines have shown remarkable efficacy, safety, and reliability in recent studies. However, the screening process for immunopotent antigenic peptides is cumbersome, limiting their widespread application. Identifying neoantigen peptides that can effectively trigger an...

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Bibliographic Details
Main Authors: Siyu Zhang, Changxin Huang, Yongqiang Li, Zhaoyang Li, Ying Zhu, Lili Yang, Haokun Hu, Quan Sun, Mengmeng Liu, Songqiang Cao
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1473145/full