Robust in vitro assay for analyzing the neutralization activity of serum specimens against hepatitis B virus

Robust in vitro assay for analyzing the neutralization activity of serum specimens against hepatitis B virus

ABSTRACTAnti-HBs is a well-known marker of protective capability against HBV. However, little is known about the association between the qAnti-HBs determined by immunoassays and the neutralization activity (NAT) derived from functional assays. We developed an in vitro assay for direct measurement of...

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Main Authors: Ya-Li Zhang, Ying Gao, Jia-Li Cao, Jing-Hua Zhao, Tian-Ying Zhang, Chuan-Lai Yang, Hua-Long Xiong, Ying-Bin Wang, Shan-Hai Ou, Tong Cheng, Chang-Rong Chen, Quan Yuan, Ning-Shao Xia
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Emerging Microbes and Infections
Subjects:
Hepatitis B virus
cell-based assay for neutralization activity against HBV
hepatitis B neutralizing antibodies
hepatitis B surface antibody
hepatitis B core antibody
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2019.1619485

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https://www.tandfonline.com/doi/10.1080/22221751.2019.1619485

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