An obligatory role of mind bomb-1 in notch signaling of mammalian development.

The Notch signaling pathway is an evolutionarily conserved intercellular signaling module essential for cell fate specification that requires endocytosis of Notch ligands. Structurally distinct E3 ubiquitin ligases, Neuralized (Neur) and Mind bomb (Mib), cooperatively regulate the endocytosis of Not...

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Bibliographic Details
Main Authors: Bon-Kyoung Koo, Mi-Jeong Yoon, Ki-Jun Yoon, Sun-Kyoung Im, Yoon-Young Kim, Cheol-Hee Kim, Pann-Ghill Suh, Yuh Nung Jan, Young-Yun Kong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2082076?pdf=render