Dual inhibition of the Echinococcus multilocularis energy metabolism

Dual inhibition of the Echinococcus multilocularis energy metabolism

Alveolar echinococcosis is caused by the metacestode stage of the zoonotic parasite Echinococcus multilocularis. Current chemotherapeutic treatment options rely on benzimidazoles, which have limited curative capabilities and can cause severe side effects. Thus, novel treatment options are urgently n...

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Bibliographic Details
Main Authors: Sheena Chaudhry, Raphael Zurbriggen, Matías Preza, Tobias Kämpfer, Marc Kaethner, Roman Memedovski, Nathalie Scorrano, Andrew Hemphill, Joseph Stone Doggett, Britta Lundström-Stadelmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Veterinary Science
Subjects:
mitochondrium
ELQ
endochin-like quinolone
malate dismutation
cytochrome bc1
electron transfer chain
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2022.981664/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2022.981664/full

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