Flow cytometric analysis of erythrocytes in paroxysmal nocturnal hemoglobinuria reveals superiority of CD59 as a diagnostic marker compared to CD55

<b>Context:</b> Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired clonal stem cell disorder characterized by complement-mediated hemolysis due to reduced expression of glycosyl phosphatidylinositol-anchored complement deactivating proteins such as CD55 and CD59 on RBC. Flow cytome...

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Bibliographic Details
Main Authors: Tembhare Prashant, Ramani Manisha, Syed Keerti, Gupta Amar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2010-10-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
Online Access:http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2010;volume=53;issue=4;spage=699;epage=703;aulast=Tembhare