Mammalian-adaptive mutation NP-Q357K in Eurasian H1N1 Swine Influenza viruses determines the virulence phenotype in mice

Mammalian-adaptive mutation NP-Q357K in Eurasian H1N1 Swine Influenza viruses determines the virulence phenotype in mice

ABSTRACTIt has recently been proposed that the Eurasian avian-like H1N1 (EA H1N1) swine influenza virus (SIV) is one of the most likely zoonotic viruses to cause the next influenza pandemic. Two main genotypes EA H1N1 viruses have been recognized to be infected humans in China. Our study finds that...

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Bibliographic Details
Main Authors: Wenfei Zhu, Zhaomin Feng, Yongkun Chen, Lei Yang, Jia Liu, Xiyan Li, Suli Liu, Lijuan Zhou, Hejiang Wei, Rongbao Gao, Dayan Wang, Yuelong Shu
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Emerging Microbes and Infections
Subjects:
Eurasian avian-like H1N1 swine influenza viruses
NP gene
NP-K357Q
pathogenicity
pandemic potential
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2019.1635873

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https://www.tandfonline.com/doi/10.1080/22221751.2019.1635873

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