Transmembrane protein 135 regulates lipid homeostasis through its role in peroxisomal DHA metabolism

Transmembrane protein 135 regulates lipid homeostasis through its role in peroxisomal DHA metabolism

Lipid analysis of transmembrane protein 135 (TMEM135) mutant mice reveals robust decreases in docosahexaenoic acid (DHA), indicating a function of TMEM135 on the export of DHA from peroxisomes that is important for maintaining lipid metabolism.

Bibliographic Details
Main Authors: Michael Landowski, Vijesh J. Bhute, Samuel Grindel, Zachary Haugstad, Yeboah K. Gyening, Madison Tytanic, Richard S. Brush, Lucas J. Moyer, David W. Nelson, Christopher R. Davis, Chi-Liang Eric Yen, Sakae Ikeda, Martin-Paul Agbaga, Akihiro Ikeda
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-04404-7

Internet

https://doi.org/10.1038/s42003-022-04404-7

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