New insights of growth hormone (GH) actions from tissue-specific GH receptor knockouts in mice

ABSTRACT In order to provide new insights into the various activities of GH in specific tissues, recent advances have allowed for the generation of tissue-specific GHR knockout mice. To date, 21 distinct tissue-specific mouse lines have been created and reported in 28 publications. Targeted tissues...

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Bibliographic Details
Main Authors: Edward O. List, Darlene E. Berryman, Elizabeth A. Jensen, Prateek Kulkarni, Savannah McKenna, John J. Kopchick
Format: Article
Language:English
Published: Brazilian Society of Endocrinology and Metabolism 2020-01-01
Series:Archives of Endocrinology and Metabolism
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972019000900557&tlng=en