Super-resolution mapping in rod photoreceptors identifies rhodopsin trafficking through the inner segment plasma membrane as an essential subcellular pathway.

Photoreceptor cells in the vertebrate retina have a highly compartmentalized morphology for efficient phototransduction and vision. Rhodopsin, the visual pigment in rod photoreceptors, is densely packaged into the rod outer segment sensory cilium and continuously renewed through essential synthesis...

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Bibliographic Details
Main Authors: Kristen N Haggerty, Shannon C Eshelman, Lauren A Sexton, Emmanuel Frimpong, Leah M Rogers, Melina A Agosto, Michael A Robichaux
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3002467