Characteristics Associated with Tumor Development in Individuals Diagnosed with Beckwith–Wiedemann Spectrum: Novel Tumor-(epi)Genotype-Phenotype Associations in the BWSp Population

Characteristics Associated with Tumor Development in Individuals Diagnosed with Beckwith–Wiedemann Spectrum: Novel Tumor-(epi)Genotype-Phenotype Associations in the BWSp Population

Beckwith–Wiedemann Spectrum (BWSp) is the most common epigenetic childhood cancer predisposition disorder. BWSp is caused by (epi)genetic changes affecting the BWS critical region on chromosome 11p15. Clinically, BWSp represents complex molecular and phenotypic heterogeneity resulting in a range of...

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Bibliographic Details
Main Authors: Kelly A. Duffy, Kelly D. Getz, Evan R. Hathaway, Mallory E. Byrne, Suzanne P. MacFarland, Jennifer M. Kalish
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Genes
Subjects:
Beckwith–Wiedemann Syndrome
Beckwith–Wiedemann Spectrum
cancer predisposition
tumor screening
hepatoblastoma
genotype-phenotype
Online Access:https://www.mdpi.com/2073-4425/12/11/1839

Internet

https://www.mdpi.com/2073-4425/12/11/1839

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