Alterations in zonal distribution and plasma membrane localization of hepatocyte bile acid transporters in patients with NAFLD

Alterations in zonal distribution and plasma membrane localization of hepatocyte bile acid transporters in patients with NAFLD

Background:. NAFLD is highly prevalent with limited treatment options. Bile acids (BAs) increase in the systemic circulation and liver during NAFLD progression. Changes in plasma membrane localization and zonal distribution of BA transporters can influence transport function and BA homeostasis. Howe...

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Bibliographic Details
Main Authors: William A. Murphy, Anna Mae Diehl, Matthew Shane Loop, Dong Fu, Cynthia D. Guy, Manal F. Abdelmalek, Georgia Sofia Karachaliou, Noora Sjöstedt, Sibylle Neuhoff, Paavo Honkakoski, Kim L. R. Brouwer
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2024-03-01
Series:Hepatology Communications
Online Access:http://journals.lww.com/10.1097/HC9.0000000000000377

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http://journals.lww.com/10.1097/HC9.0000000000000377

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