A high‐throughput ChIP‐Seq for large‐scale chromatin studies

A high‐throughput ChIP‐Seq for large‐scale chromatin studies

Abstract We present a modified approach of chromatin immuno‐precipitation followed by sequencing (ChIP‐Seq), which relies on the direct ligation of molecular barcodes to chromatin fragments, thereby permitting experimental scale‐up. With Bar‐ChIP now enabling the concurrent profiling of multiple DNA...

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Bibliographic Details
Main Authors: Christophe D Chabbert, Sophie H Adjalley, Bernd Klaus, Emilie S Fritsch, Ishaan Gupta, Vicent Pelechano, Lars M Steinmetz
Format: Article
Language:English
Published: Springer Nature 2015-01-01
Series:Molecular Systems Biology
Subjects:
ChIP‐Seq
chromatin
high‐throughput
histone marks
histone methyltransferase
Online Access:https://doi.org/10.15252/msb.20145776

Internet

https://doi.org/10.15252/msb.20145776

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