Protein-RNA interaction dynamics reveal key regulators of oncogenic KRAS-driven cancers

Abstract KRAS is one of the most frequently mutated oncogenes across various cancers. Oncogenic KRAS mutations rewire cellular signaling, leading to significant alterations in gene expression. RNA-binding proteins (RBPs) play a pivotal role in gene expression regulation by post-transcriptionally con...

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Bibliographic Details
Main Authors: Ka-Yun Ban, Yong-woo Na, Juhan Song, Jong-Seo Kim, Jimi Kim
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-78333-2