Intra-articular Adenosine, Lidocaine and Magnesium (ALM) solution decreases postoperative joint fibrosis in an experimental knee implant model

Intra-articular Adenosine, Lidocaine and Magnesium (ALM) solution decreases postoperative joint fibrosis in an experimental knee implant model

Abstract Background There is currently no drug therapy to prevent arthrofibrosis following knee surgery. We aimed to determine if the anti-ischemic and anti-inflammatory drug adenosine, lidocaine and Mg2+ (ALM), reduces surgery-related arthrofibrosis in a rat model of knee implant surgery. Methods M...

Full description

Bibliographic Details
Main Authors: Jodie L. Morris, Hayley L. Letson, Peter McEwen, Erik Biros, Constantin Dlaska, Kaushik Hazratwala, Matthew Wilkinson, Geoffrey P. Dobson
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Translational Medicine Communications
Subjects:
Total knee arthroplasty
Stiffness
Arthrofibrosis
Inflammation
Online Access:https://doi.org/10.1186/s41231-021-00084-3

Internet

https://doi.org/10.1186/s41231-021-00084-3

Similar Items