Current progress and outcomes of clinical trials on using epidermal growth factor receptor-tyrosine kinase inhibitor therapy in non-small cell lung cancer patients with brain metastases

Current progress and outcomes of clinical trials on using epidermal growth factor receptor-tyrosine kinase inhibitor therapy in non-small cell lung cancer patients with brain metastases

Non-small cell lung cancer (NSCLC) continues to be one of the major causes of cancer-related deaths worldwide, and brain metastases are the major cause of death in NSCLC patients. With recent advances in understanding the underlying molecular mechanism of NSCLC development and progression, mutations...

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Bibliographic Details
Main Authors: Ling-Ling Kong, Lin-Lin Wang, Li-Gang Xing, Jin-Ming Yu
Format: Article
Language:English
Published: Wiley 2017-12-01
Series:Chronic Diseases and Translational Medicine
Subjects:
Non-small cell lung cancer
Brain metastases
Epidermal growth factor receptor mutation
Tyrosine kinase inhibitors
Therapeutic outcomes
Online Access:http://www.sciencedirect.com/science/article/pii/S2095882X17300762

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http://www.sciencedirect.com/science/article/pii/S2095882X17300762

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