Abnormal anxiety- and depression-like behaviors in mice lacking both central serotonergic neurons and pancreatic islet cells

Abnormal anxiety- and depression-like behaviors in mice lacking both central serotonergic neurons and pancreatic islet cells

Dysfunction of central serotonin (5-HT) system has been proposed to be one of the underlying mechanisms for anxiety and depression, and the association of diabetes mellitus and psychiatric disorders has been noticed by the high prevalence of anxiety/depression in patients with diabetes mellitus. Thi...

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Bibliographic Details
Main Authors: Yun-Fang eJia, Ning-Ning eSong, Rong-Rong eMao, Jin-Nan eLi, Qiong eZhang, Ying eHuang, Lei eZhang, Hui-Li eHan, Yu-Qiang eDing, Lin eXu
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Anxiety
Depression
Diabetes Mellitus
Serotonin
adult neurogenesis
Pet1
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00325/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00325/full

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