Adenosine A Agonist Administration Improves Islet Transplant Outcome: Evidence for the Role of Innate Immunity in Islet Graft Rejection

Adenosine A Agonist Administration Improves Islet Transplant Outcome: Evidence for the Role of Innate Immunity in Islet Graft Rejection

Activation of adenosine A 2A receptors inhibits inflammation in ischemia/reperfusion injury, and protects against cell damage at the injury site. Following transplantation 50% of islets die due to inflammation and apoptosis. This study investigated the effects of adenosine A 2A receptor agonists (AT...

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Bibliographic Details
Main Authors: Preeti Chhabra, Kunjie Wang, Qiang Zeng, Mladen Jecmenica, Linda Langman, Joel Linden, Robert J. Ketchum, Kenneth L. Brayman
Format: Article
Language:English
Published: SAGE Publishing 2010-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368910X491806

Internet

https://doi.org/10.3727/096368910X491806

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