Revisiting the Mongolian Gerbil Model for Hepatitis E Virus by Reverse Genetics

Revisiting the Mongolian Gerbil Model for Hepatitis E Virus by Reverse Genetics

ABSTRACT Hepatitis E virus (HEV) is a major cause of acute viral hepatitis in humans. A convenient small mammalian model for basic research and antiviral testing is still greatly needed. Although a small rodent, the Mongolian gerbil, was reported to be susceptible to swine genotype-4 HEV infection,...

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Bibliographic Details
Main Authors: Ling-Dong Xu, Fei Zhang, Chu Chen, Lei Peng, Wen-Ting Luo, Ruiai Chen, Pinglong Xu, Yao-Wei Huang
Format: Article
Language:English
Published: American Society for Microbiology 2022-04-01
Series:Microbiology Spectrum
Subjects:
hepatitis E virus (HEV)
Mongolian gerbil
innate immunity
antivirals
interferon
reverse genetics
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02193-21

Internet

https://journals.asm.org/doi/10.1128/spectrum.02193-21

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