Mesenchymal stem cells pretreated with proinflammatory cytokines accelerate skin wound healing by promoting macrophages migration and M2 polarization

Mesenchymal stem cells pretreated with proinflammatory cytokines accelerate skin wound healing by promoting macrophages migration and M2 polarization

Introduction: Numerous studies have shown that mesenchymal stem cells (MSCs) promote cutaneous wound healing via paracrine signaling. Our previous study found that the secretome of MSCs was significantly amplified by treatment with IFN-γ and TNF-α (IT). It has been known that macrophages are involve...

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Bibliographic Details
Main Authors: Chenyang Liu, Yichi Lu, Pan Du, Fengbo Yang, Peng Guo, Xiaoyu Tang, Ling Diao, Guozhong Lu
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Regenerative Therapy
Subjects:
Mesenchymal stem cell
IFN-γ and TNF-α
Macrophages
Migration
M2 polarization
Wound healing
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320422000621

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http://www.sciencedirect.com/science/article/pii/S2352320422000621

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