Distinct and sequential re-replication barriers ensure precise genome duplication.

Distinct and sequential re-replication barriers ensure precise genome duplication.

Achieving complete and precise genome duplication requires that each genomic segment be replicated only once per cell division cycle. Protecting large eukaryotic genomes from re-replication requires an overlapping set of molecular mechanisms that prevent the first DNA replication step, the DNA loadi...

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Bibliographic Details
Main Authors: Yizhuo Zhou, Pedro N Pozo, Seeun Oh, Haley M Stone, Jeanette Gowen Cook
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-08-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008988

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https://doi.org/10.1371/journal.pgen.1008988

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