Isoform of APOE with retained intron 3; quantitation and identification of an associated single nucleotide polymorphism

<p>Abstract</p> <p>Background</p> <p>Alleles of apolipoprotein E (<it>APOE</it>) are the major genetic risk factor for late onset Alzheimer's Disease (LOAD). Recently, an <it>APOE </it>splice variant that retains intron 3 (<it>APOE-I3&...

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Bibliographic Details
Main Authors: Dieter Laura S, Estus Steven
Format: Article
Language:English
Published: BMC 2010-09-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/5/1/34