Macrophages disseminate pathogen associated molecular patterns through the direct extracellular release of the soluble content of their phagolysosomes

Macrophages disseminate pathogen associated molecular patterns through the direct extracellular release of the soluble content of their phagolysosomes

The detection of conserved motifs by pattern recognition receptors is a crucial component of the innate detection of pathogens and danger signals via conserved pattern recognition receptors. Here the authors define a pathway that transfers partially digested material from the phagolysosomal pathway...

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Bibliographic Details
Main Authors: Catherine J. Greene, Jenny A. Nguyen, Samuel M. Cheung, Corey R. Arnold, Dale R. Balce, Ya Ting Wang, Adrian Soderholm, Neil McKenna, Devin Aggarwal, Rhiannon I. Campden, Benjamin W. Ewanchuk, Herbert W. Virgin, Robin M. Yates
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-30654-4

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https://doi.org/10.1038/s41467-022-30654-4

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