N-Butanol Extract of Modified You-Gui-Yin Attenuates Osteoclastogenesis and Ameliorates Osteoporosis by Inhibiting RANKL-Mediated NF-κB Signaling

N-Butanol Extract of Modified You-Gui-Yin Attenuates Osteoclastogenesis and Ameliorates Osteoporosis by Inhibiting RANKL-Mediated NF-κB Signaling

Postmenopausal Osteoporosis (PMOP) is the most prevalent primary osteoporosis, attributable to an imbalance in osteoblast and osteoclast activity. Modified You-Gui-Yin (MYGY), a traditional Chinese herbal formula, is able to effectively treat PMOP, while the critical components and pharmacological m...

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Bibliographic Details
Main Authors: Qinghe Zeng, Rui Xu, Houfu Ling, Shan Zhao, Xu Wang, Wenhua Yuan, Mancang Gu, Taotao Xu, Pinger Wang, Hongfeng Ruan, Hongting Jin, Hangbo Qu, Fusheng Ye, Jiali Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Endocrinology
Subjects:
N-butanol extraction
Modified You-Gui-Yin
postmenopausal osteoporosis
osteoclast formation
NF-κB pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.925848/full

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https://www.frontiersin.org/articles/10.3389/fendo.2022.925848/full

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