PEX5 and ubiquitin dynamics on mammalian peroxisome membranes.

Peroxisomes are membrane-bound organelles within eukaryotic cells that post-translationally import folded proteins into their matrix. Matrix protein import requires a shuttle receptor protein, usually PEX5, that cycles through docking with the peroxisomal membrane, ubiquitination, and export back in...

Full description

Bibliographic Details
Main Authors: Aidan I Brown, Peter K Kim, Andrew D Rutenberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3894153?pdf=render