Temozolomide post pazopanib treatment failure in patients with advanced sarcoma: A case series.

Sarcomas are rare, heterogeneous tumors for which prognosis remains dismal in patients with advanced disease. Pazopanib, a vascular endothelial growth factor receptor inhibitor, has shown modest efficacy in patients with soft tissue sarcoma who fail cytotoxic chemotherapy. The cytotoxic agent temozo...

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Bibliographic Details
Main Authors: Manojkumar Bupathi, John L Hays, James L Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5687737?pdf=render