Ceramide as a Target of Marine Triterpene Glycosides for Treatment of Human Myeloid Leukemia

Acute myeloid leukemia (AML) is a heterogeneous myeloid clonal disorder exhibiting the accumulation of immature myeloid progenitors in the bone marrow and peripheral blood. Standard AML therapy requires intensive combination chemotherapy, which leads to significant treatment-related toxicity. The se...

Full description

Bibliographic Details
Main Authors: Seong-Hoon Yun, Sung-Won Shin, Valentin A. Stonik, Joo-In Park
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/14/11/205